Vitamin K antagonists, such as warfarin, have an unpredictable pharmacokinetic profile and numerous food and drug interactions ... key proteases in the coagulation cascade: thrombin and factor ...

and initiate the activation of the coagulation cascade when they come into contact with blood. Analyses by the study authors confirm that mucosal bleeding in the mouth of these patients is indeed ...

Coagulant Therapeutics—a privately held biotech company of seasoned drug developers specializing in biologics and the coagulation cascade—is here to fill that void. Drawing on over 100 years ...