Which will succeed in that plight, though? That's what we're left to decide as we dive into our NFL Week 16 predictions with picks straight-up and against the spread for the full 16-game slate.

Ready? Let's jump in. All NFL betting courtesy of SportsLine consensus. Which picks can you make with confidence in Week 16? And which Super Bowl contender goes down hard? Visit SportsLine ...

There’s nothing better in sports than a good rivalry, and until the Bills beat the Chiefs in a postseason game, the best one in the NFL remains ... and then again in Week 18 against Cincinnati ...

Ahead of NFL free agency, several big-players could end up as cap casualties as teams release veterans to get their financial ...

It is beginning to look a lot like playoff time. The second NFL season is on the horizon, which means the final three weeks of the regular season are approaching quickly. This year’s NFL lineup ...

Check out The Arizona Republic's NFL playoff picks and NFL playoff predictions for both ... This team has won seven straight ...

It’s one of the worst-kept secrets in the NFL that the Raiders need a QB, and they were aggressive in their effort to land ...

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The NFL playoffs continue ... beating the Chiefs this week, either. Will we be wrong again? Kansas City is a big favorite after having the bye week to rest and prepare. The Chiefs beat the Texans in ...

The NFL playoff schedule continues with two games today ... This team has won seven straight games, including a 36-33 win over the Eagles in Week 16 at home. But, this game is being played in ...

Los Angeles Times NFL writer Sam Farmer examines the matchups ... more than 100 yards against them in the opening quarter in Week 16, the Commanders clamped down on him the rest of the way.