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Circulating endothelial cell enumeration demonstrates prolonged endothelial damage in recipients of myeloablative allogeneic stem cell transplantation. Haematologica 2015; 100: e246–e249.
Scientists have developed a new understanding of how the first blood cells form during human development as they transition from endothelial cells to form blood cells of different types.
Pterygium excision with intraoperative mitomycin C may spur central endothelial cell loss, a study found. "Because proximity of the application site to the cornea may have an effect on the corneal ...
Graft failure in any situation can happen due to inherent defects in the donor graft or pre-existing pathology in the recipient. Inherent graft issues such as low endothelial cell count, surgical ...
The transient reductions in endothelial cell count and CCT following SLT returned to baseline levels 1 month after the procedure.
Endothelial dysfunction can be caused by several conditions including diabetes or hypertensio, as well as factors such as smoking.
Instead the study found that a patient's endothelial cell count six months post-cornea transplant is a better indicator of subsequent failure of the graft rather than the donor's cell count.
How are endothelial cells activated in the first place? Shi et al. 2022 suggests there may be a connection between increased circulation of antiphospholipid autoantibodies and endothelial activation.
Overall, the 10-year results continued the trend found at 5 years, namely that older donor tissue was associated with a lower endothelial cell count and a higher rate of graft failure.
Topol and his colleagues found the abnormal cells using a new technology that sorts blood cells so well that it can detect a single endothelial cell among millions of blood cells.
A group at Scripps Translational Science Institute is developing a blood test that uses circulating endothelial cells to spot a plaque rupture in progress.
Patients will receive four intracameral TTHX1114 injections at 7-day intervals. The study’s primary endpoint is the change in corneal endothelial cell count from baseline to Day 56.