Stable cell–cell adhesion is essential for maintaining tissue integrity, but cells are also able to relocate, implying the existence of mechanisms for coordinating cell adhesion and movement.

Notably, targeting of Sec8 to the apical cell surface does not require a docked basal body; we frequently observed aberrant, Sec8-positive structures projecting apically in Dvl morphants, and such ...

Epithelial cells typically exhibit apicobasal polarity: their apical surfaces contact other cells or the environment, whereas their basal surfaces are separated from neighboring cells by a wall ...

At the 16-cell stage, the different subtypes of RNA, named rRNAs, mRNAs and tRNAs, are sorted to the two ends of a cell called apical and basal side.

Pools of stem cells in the apical meristems of plants are key to continued growth and development. ... and this gradient is essential for the stem cell specification and the apical-basal patterning of ...

Here, we uncover apical-to-basal RNA asymmetries in outer blastomeres of 16-cell stage mouse preimplantation embryos.” These findings may lead to the development of new regenerative treatments.

"Ribonucleic acid, RNA, plays a key role here. At the 16-cell stage, the different subtypes of RNA, named rRNAs, mRNAs and tRNAs, are sorted to the two ends of a cell called apical and basal side.

Intestinal organoids that are classically grown in 3-D matrices are cystic, which means that they have a monolayer of epithelial cells with fluid inside. The cells interact with the matrix on the ...

The basal cell layer consists of about 5%–10% of melanocytes cells. Although every person possesses a unique skin color, the melanocyte density is similar in all types of skin.

Specifically, the researchers deleted the BRCA1 gene in mouse basal stem cells or luminal intermediate cells. They discovered that although BRCA1 deletion caused tumors to form from both basal ...