The establishment and maintenance of apical–basal cell polarity is essential for the functionality of glandular epithelia. Cell polarity is often lost in advanced tumours correlating with ...

At the 16-cell stage, the different subtypes of RNA, named rRNAs, mRNAs and tRNAs, are sorted to the two ends of a cell called apical and basal side.

Here, we uncover apical-to-basal RNA asymmetries in outer blastomeres of 16-cell stage mouse preimplantation embryos.” These findings may lead to the development of new regenerative treatments.

Epithelial cells typically exhibit apicobasal polarity: their apical surfaces contact other cells or the environment, whereas their basal surfaces are separated from neighboring cells by a wall ...

Northwestern Medicine scientists have discovered a previously unknown process used by epithelial cells to alleviate ...

Pools of stem cells in the apical meristems of plants are key to continued growth and development. ... and this gradient is essential for the stem cell specification and the apical-basal patterning of ...

Intestinal organoids that are classically grown in 3-D matrices are cystic, which means that they have a monolayer of epithelial cells with fluid inside. The cells interact with the matrix on the ...

The basal cell layer consists of about 5%–10% of melanocytes cells. Although every person possesses a unique skin color, the melanocyte density is similar in all types of skin.