The researchers started by making mouse iPSCs the usual way, except for one change: they swapped out Sox2, one of the Yamanaka factors, for the corresponding Sox gene from choanoflagellates.

This unexpected discovery challenges a longstanding belief that these genes evolved exclusively within animals. "By successfully creating a mouse using molecular tools derived from our single ...

This reprogramming resulted in the mouse cells transforming into stem cells, showcasing how genes older than multicellular ...

In an incredible breakthrough, scientists have created a mouse using ancient genetic tools older than animal life. By taking a gene from single-celled lifeforms and introducing it into mouse cells ...

Around 700 million years ago, the animal kingdom began to branch off from single-celled organisms. Now, scientists have uncovered molecular tools that could have assisted the leap — and ...

Scientists have raised the first viable mouse with two male parents into adulthood after editing imprinting genes.

De-extinction startup Colossal Biosciences has gene-edited mice to have mammoth-like features, creating what the company calls the Colossal Woolly Mouse. The lab mice, which have been modified to ...

Temporal and spatial control of gene expression in the mouse can be achieved using binary transgenic systems, in which gene expression is controlled by the interaction of an effector protein ...

This unexpected discovery challenges a longstanding belief that these genes evolved exclusively within animals. “By successfully creating a mouse using molecular tools derived from our single-celled ...