In Your Friendly Neighborhood Spider-Man Norman Osborn is voiced by actor Colman Domingo, who was recently seen as John "Divine G" Whitfield in Sing Sing. When Jeff Trammell was asked about the changes made to the character the showrunner teased viewers should not bring in their prior knowledge about the character. Here is what he said:

We've only seen two episodes of Your Friendly Neighborhood Spider-Man, but there's already speculation that Norman Osborn will eventually become the Green Goblin. Now, Jeff Trammell has weighed