On their own, however, polymerases aren't good at staying on the DNA strand. They require CTF18-RFC in humans and Ctf18-RFC in yeast to thread a ring-shaped clamp onto the DNA leading strand, and ...

Great recipes require the perfect combination of ingredients—biotechnology recipes are no exception. Researchers from Osaka ...

Think yeast just belongs in the kitchen ... checkpoint genes, and DNA repair genes — the obvious question is, what comes next? The hope is that this knowledge will help scientists not only ...

Researchers from Osaka Metropolitan University have discovered the ideal genetic “recipe” to turn yeast into a tiny yet ...

In yeast, however, binding of Rad51 to ssDNA is enhanced by the proteins Rad52 and the complex Rad55-Rad57. Once access has been gained, Rad51 polymerizes on the DNA strand to form what is called ...

The often-mentioned fact that humans and chimpanzees are 99.9 percent identical in their DNA is hard to accept for ... inserted into the cells of a lowly yeast -- and it functioned perfectly ...

Researchers have engineered yeast to efficiently convert methanol into D-lactic acid, a key compound for biodegradable plastics and pharmaceuticals. By optimizing gene and promoter combinations, they ...

DNA ligase IV is a 911-amino acid polypeptide that plays a role in the repair of double-strand DNA breaks via non-homologous end joining (NHEJ). Yeast cells contain 2 separately encoded DNA ligases, ...

The researchers identified "HOT" regions—sections of the DNA that are bound by many different ... of how genes are regulated in fission yeast but could also reveal insights into gene regulation ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...

Recombinant yeast cells can be used as a vector to produce proteins that would normally be found in animals or plants. Recombinant yeast cells are used during DNA Recombinant technology as they ...