On their own, however, polymerases aren't good at staying on the DNA strand. They require CTF18-RFC in humans and Ctf18-RFC in yeast to thread a ring-shaped clamp onto the DNA leading strand, and ...

Gene regulation underpins nearly every biological process—from cell development to responses to environmental changes, and understanding it can provide insights into cancer and other diseases. Now, ...

Think yeast just belongs in the kitchen ... checkpoint genes, and DNA repair genes — the obvious question is, what comes next? The hope is that this knowledge will help scientists not only ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...

In yeast, however, binding of Rad51 to ssDNA is enhanced by the proteins Rad52 and the complex Rad55-Rad57. Once access has been gained, Rad51 polymerizes on the DNA strand to form what is called ...

so he planned to follow familiar procedures like extracting black widow DNA, isolating and copying the silk genes, and pasting them into a yeast strain. Easy peasy, right? Naturally, good science ...

The often-mentioned fact that humans and chimpanzees are 99.9 percent identical in their DNA is hard to accept for ... inserted into the cells of a lowly yeast -- and it functioned perfectly ...

DNA ligase IV is a 911-amino acid polypeptide that plays a role in the repair of double-strand DNA breaks via non-homologous end joining (NHEJ). Yeast cells contain 2 separately encoded DNA ligases, ...

Recombinant yeast cells can be used as a vector to produce proteins that would normally be found in animals or plants. Recombinant yeast cells are used during DNA Recombinant technology as they ...

Fzata, Inc. announces the execution of a clinical trial agreement with the National Institutes of Health (NIH) to sponsor a ...