Medically reviewed by Marla Anderson, MD The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for ...

A first-ever analysis of the whole Greenland shark genome gives researchers a couple of clues to their longevity.

People with the rare Li-Fraumeni syndrome (LFS) have a high risk of developing cancer. Almost all those affected will develop ...

When the TP53 gene was disrupted in these cells, they grew faster and became more resistant to radiation, reinforcing the idea that p53 helps prevent cancerous growth. Another key discovery was a ...

In particular, they found that the sharks carried an altered version of the TP53 gene, which helps suppress tumors and repair DNA. Those findings, published in a preprint paper in September ...

The TP53 gene helps stop the growth of cells that have damaged DNA. An inherited TP53 mutation causes Li-Fraumeni syndrome, a disorder that ups your chances of breast cancer, leukemia, brain ...

Researchers have discovered race-associated molecular differences in tumors that may impact the way patients with pancreatic ...

Genetic and genomic testing guide breast cancer risk assessment and treatment, as discussed by Dr. Mark Robson at the Miami ...

When the TP53 gene was disrupted in these cells, they grew faster and became more resistant to radiation, reinforcing the idea that p53 helps prevent cancerous growth. Another key discovery was a ...

In many cancer types, the TP53 gene is often mutated or deleted, which inactivates the tumour suppression activity of the p53 protein. However, loss of p53 tumour-suppressor activity can also ...

This surge reflects the increasing reliance on genetic diagnostics for identifying hereditary diseases, guiding cancer ...

Genetic abnormalities, including deletions (5q-, 7q-, 20q-) and mutations in splicing genes (SF3B1, SRSF2), epigenetic regulators (ASXL1, TET2), and tumor suppressors (TP53), guide prognosis and ...