These large, mysterious creatures are the longest-living vertebrates on the planet—and their genomes could contain clues to ...

A first-ever analysis of the whole Greenland shark genome gives researchers a couple of clues to their longevity.

The Greenland shark, a slow-moving giant of the North Atlantic and Arctic Oceans, holds the record as the longest-lived ...

When the TP53 gene was disrupted in these cells, they grew faster and became more resistant to radiation, reinforcing the idea that p53 helps prevent cancerous growth. Another key discovery was a ...

Researchers have discovered race-associated molecular differences in tumors that may impact the way patients with pancreatic ...

The TP53 gene helps stop the growth of cells that have damaged DNA. An inherited TP53 mutation causes Li-Fraumeni syndrome, a disorder that ups your chances of breast cancer, leukemia, brain ...

A new type of cluster analysis makes customised cancer screening tests possible. People with the rare Li-Fraumeni syndrome (LFS) have a high risk of developing cancer. Almost all those affected will ...

In many cancer types, the TP53 gene is often mutated or deleted, which inactivates the tumour suppression activity of the p53 protein. However, loss of p53 tumour-suppressor activity can also ...

For example, Asian elephants, a species with notably low cancer prevalence, have over 20 copies of a tumour suppressor gene ...

In episode four of Chat!DNA, an interview series by BGI Genomics, we feature Lin Cong, whose research on colorectal cancer, ...

You must go for follow-up screening, ” admonishes Dr Kavitha Rethanavalan, consultant clinical geneticist at Kuala Lumpur ...