TGF-β signaling pathway mediates neuronal-intestinal mitochondrial stress response and lipid metabolism, finds study
Transforming growth factor-beta (TGF-β), a well-known morphogen, is recognized for its role in regulating growth and ...
Discovery of C-reactive protein's inflammatory pathway in diabetic kidneys offers new treatment avenues
A research team from the School of Chinese Medicine in the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) ...
Nature6mon
Inhibition of JNK Enhances TGF-β1-Activated Smad2 Signaling in Mouse Embryonic Lung
Because a number of cell-specific interactions have been described between TGF-β1-driven Smad signaling and the c-Jun N-terminal kinase (JNK) pathway, we have investigated the effects of JNK ...
Yahoo Finance19d
IO Biotech Announces New Preclinical Data for Additional Pipeline Candidate Presented at the AACR-IO Conference
Transforming Growth Factor Beta (TGF-β ... “Unlike other existing approaches that aim at inhibiting the TGFβ signaling systemically, our strategy uniquely targets TGFβ+ cells that are ...
Yahoo Finance14d
Keros Therapeutics Announces Participation at Upcoming Healthcare Conferences
About Keros Therapeutics, Inc. Keros is a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapeutics to treat a wide range of patients with disorders that ...
Phys.org22d
Combined organ-specific mRNA and lipid nanoparticle therapy could repair damaged lungs
the mRNA then instructs the immune system to create transforming growth factor beta (TGF-b), a signaling molecule vital for the body to repair tissue. "This research marks the birth of a new mRNA ...