VISUALIZING VESICLES:© 2003 Nature Publishing GroupIn A, researchers used a fluorescent protein (synaptopHluorin) to visualize synaptic vesicle movement. Some vesicles stay open briefly before ...

Imaging synaptic vesicles in 3D Date: December 3, 2024 Source: Max Delbrück Center for Molecular Medicine in the Helmholtz Association Summary: Researchers have used cryo-electron tomography to ...

Dynamic regulation of vesicle pools in a detailed spatial model of the complete synaptic vesicle cycle. Science Advances , 2025; 11 (22) DOI: 10.1126/sciadv.adq6477 Cite This Page : ...

Homeostatic plasticity, the brain's method of preserving equilibrium in neural circuits, relies heavily on spontaneous ...

What Exactly is the Synaptic Vesicle Cycle? The vesicle cycle describes how neurotransmitters (chemical signals) are released at synapses, the junctions between nerve cells, to transmit information.

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

Broken connections between brain cells play a critical role in multiple neurodegenerative conditions, including Parkinson's ...

Once the VMAT has packed the vesicle with monoamines, the vesicle can then move toward the synaptic gap, into where it releases the chemical compounds. VMATs belong to the SLC18 family of ...

Researchers at the Max Delbrück Center have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain.