Figure 4: The structural basis for dual DNA and RNA recognition by TDP43 and by the NF-κB subunit p50. The evolutionary forces driving the structure and function of DRBPs are complex, but ...

These interactions may also stabilize the initial DNA bubble ... consistent with its function in RNA separation. Nucleic acids were present, but partial mobility prevented structure completion.

This RNA does not code for proteins and is copied from sections of the genome once believed to be "junk DNA ... work showing that structure plays a role in the function of other classes of ...

This discovery, along with the identification of other nitrogenous bases, laid the foundation for our understanding of DNA and RNA structure. Cytosine can be ... typically single-stranded and serves ...

Researchers have been learning more about how modifications in the shape of an RNA molecule change its function. Recent work has used HIV as a model to show that the structure of an RNA molecule can ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

One of the main challenges is understanding the complex interplay between guanine and the other nucleobases in the context of DNA and RNA structure and function. Investigating how modifications to ...

Basic Research Guides the Development of New Therapeutic Strategies Knowledge of the structure and function of catalytic RNA is important for improving existing ribozymes and developing new ones.

Genes contain instructions for protein production, and the central dogma of biology states that this information flows from DNA ... specific RNA molecules are essential for cell function.

This RNA does not code for proteins and is copied from sections of the genome once believed to be “junk DNA.” Since then ... Inspired by historical work showing that structure plays a role in the ...