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Unlike random heteropolymers, natural proteins fold into unique ordered structures. Understanding how these are encoded in amino-acid sequences is complicated by energetically unfavourable non ...
SCOPER has simplified it significantly. Say you want to study a new RNA: First, put the nucleotide sequence into one of the open-source, AI-based structure prediction tools available today.
The spike protein’s amino acid sequence, its secondary structure patterns, and its intricate three-dimensional folds are all featured. The resulting piece is a form of counterpoint music, ...
While recent breakthroughs such as AlphaFold3 have revolutionized protein and RNA structure prediction, they currently fail to reliably generate correct G-quadruplex structures from sequence alone.
A computer-generated Voronoi pattern had an 82 percent match with the pattern found in sea urchin skeletons. This arrangement, the team suspects, yields a strong yet lightweight skeletal structure.