Form of B12 deficiency in cerebral spinal fluid found to negatively affect the central nervous system
The team conducted a spinal tap to analyze the patients' cerebral spinal fluid. What came back was a surprise—the patient had ...
Pharmaceutical Technology on MSN9d
Health Canada approves Biogen’s Skyclarys for Friedreich’s ataxia
Health Canada has granted approval for Biogen’s Skyclarys (omaveloxolone) to treat Friedreich’s ataxia (FA), a rare, ...
Nature25d
Spinocerebellar ataxia articles from across Nature Portfolio
Neuronal atrophy early in a mouse model of spinal cerebellar ataxia 1 may represent an adaptive mechanism that restores the density of potassium channels in Purkinje neurons, thus normalizing ...
Nature1y
Diagnosis and treatment of Friedreich ataxia: a European perspective
Sagittal and axial MRI scans in patients with Friedreich ataxia show thinning of the cervical spinal cord, and might also show signal abnormalities in the posterior and lateral columns.
The American Journal of Managed Care9d
Shaping Gene Therapy Approaches in Neuromuscular Disease
Adeno-associated virus (AAV)–mediated gene therapy was one of the focal points of this year's Muscular Dystrophy Association conference. Here, Barry Byrne, MD, PhD, University of Florida, speaks to ...
Medindia10d
SKYCLARYS (omaveloxolone) Approval by Health Canada Ushers in a New Era for Friedreich's Ataxia Treatment in Canada
As the only approved treatment to address disease progression, SKYCLARYS addresses a long-standing gap in the care of Canadians living with Friedreich's ataxia Friedreich's ...