Although only a few rRNA molecules are present in each ribosome, these molecules make up about half of the ribosomal mass. The remaining mass consists of a number of proteins — nearly 60 in ...
However, the infection did modify the underlying molecular structure of the ribosome, leading to increased poxvirus protein translation. Genetic knockout screens coupled with metabolic assays ...
As they are being synthesized, these nascent proteins simultaneously attempt to fold while still associated with their parent ribosome, referred to as co-translational protein folding ...
A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes. Dan is a News Editor at The Scientist. He writes and ...
The researchers visualized translation, including ribosome pauses, by using the intensity of GFP-tagged antibodies on the polypeptide to measure polypeptide elongation. As Tanenbaum and his team ...
Shah and colleagues take advantage of the presence of maternal and somatic ribosomes in zebrafish and confirm their differential expression during development. The authors convincingly show that ...
The rRNA molecules fold into complex secondary and tertiary structures, forming domains and motifs that are essential for ribosome function. The rRNA structures also provide binding sites for ...