Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protein that binds to the LDL receptor on hepatocytes, promoting its internalization and degradation within the cell. [Repatha package ...

The FDA has approved Repatha (evolocumab) as an adjunct to diet and other LDL-C-lowering therapies in patients 10 years of age and older with HeFH.

Leqvio (inclisiran) and Repatha (evelocumab) are prescription injectable medications used to treat high cholesterol. They specifically target low-density lipoprotein cholesterol (LDL-C), or "bad ...

Amgen may face yet another setback with its controversial Repatha cholesterol-lowering drug because an influential nonprofit may soon lower its value rating for the medicine. In a new report, the ...

Heart experts had high expectations for Repatha, and a related drug called alirocumab (Praluent). Both belong to a new type of medication, called PCSK9 inhibitors, that work differently than statins.

The size of the benefit is about the same as is achieved with statins. That reduction in risk is meaningful – but no new records on risk reduction were set. Third, this study raises the issue of ...