Adjacent ribose nucleotide bases are chemically attached to one another in a chain via chemical bonds called phosphodiester bonds. Unlike DNA, RNA is usually single-stranded. Additionally ...

SARS-CoV-2 secondary structure shapes mutation frequencies, constraining viral evolution models predicting fitness can benefit from integrating secondary structure data.

Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a ... which are specified by three-nucleotide mRNA sequences called codons. Each codon represents a particular amino ...

The replication of the Nipah virus's genetic material in infected cells has been demonstrated for the first time by ...

One type of mutation, called a point mutation, occurs when a single nucleotide is changed. In RNA, a point mutation can involve the substitution of uracil with another nucleobase, such as cytosine (C) ...

ProQR Therapeutics NV. (Nasdaq: PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies based on its proprietary Axiomer RNA editing technology platform, today ...

RNA polymerase enzymes read the DNA sequence and synthesize ... DNA mutations are changes in the nucleotide sequence of the DNA molecule. Mutations can occur spontaneously due to errors during DNA ...

Nucleotide exchange factor SIL1 is an important regulator of ... SIL1-specific small interfering RNA was transfected into two breast cancer cell lines, MCF7 and MDA-MB-231, to generate SIL1 knockdown ...