1, 2, 3 For example, Dicer1 (an RNase III enzyme required for miRNA processing ... 5 and Sertoli cell function and survival; 6 the deficiency in Drosha (a nuclear RNase III enzyme responsible ...

miRNA functions as a guide molecule in post-transcriptional ... (pri-miRNAs), which are first cropped by RNase-III-type enzyme Drosha to release the hairpin intermediates (pre-miRNAs) in the ...

A schematic diagram ... complex (RISC) and, from there, interfere with host gene expression (Figure 3). FIGURE 3. Cutting of precursor microRNA (pre-miRNA) by the nucleases Dicer or Drosha ...