Protein kinase research presents an opportunity to explore molecular targets in the body to treat diseases like cancer and ...

Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions.

Researchers at St. Jude Children’s Research Hospital identified a panel of 27 serum proteins that accurately predicted ...

In a recent study published in Nature Communications, researchers from the University of Virginia introduced a novel method ...

Basecamp says that BaseFold builds on that model, which predicts the 3D structure of a protein based on its amino acid sequence, by layering in a foundational dataset (BaseGraph) that considers ...

We demonstrate that modeling and simulation can teach us how to improve an experimental design with a low success rate and low RDR (Fig. 2a,b, I).In this experimental design, a complex mixture of ...

A detailed quantitative model of signaling by IRE1 sheds light on the mechanism of its activation by endoplasmic reticulum stress and addresses a long-standing controversy in the field. In ...

Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity. A ...