Diagram demonstrating the functions of the new liver perfusion machine USZ/beamue The machine was developed and tested out using pig livers, with the team able to demonstrate the viability of the ...

Hypothermic machine perfusion may improve outcomes after transplantation, ... Figure 1 shows a flow diagram of the 336 kidney pairs (672 recipients) included in our analysis.

The perfusion machine was developed as an alternative solution to current clinical practice for liver transplants, which stores the organ on ice for no more than around 12 hours.

The machine also gave a low dose of immunosuppressive drugs and blood to the organ to keep it in an optimal state. The machine preserved the liver for 68 hours, nearly three days outside the body.

Two years ago, the Liver4Life research team used the system to sustain a liver outside of the body for seven days, setting the stage for an actual human transplant.The perfusion device works by ...

The Liver4Life research team owes its perfusion machine, which was developed in house, to the fact that it became possible to implant a human organ into a patient after a storage period of three ...

A liver hooked up to the perfusion machine. Image: (USZ) That said, the livers lost weight during the seven days, dropping to around 25 percent of their original mass.

The existing technology works through perfusion, which is keeping the liver’s blood vessels open and active with a circulation of body-temperature blood or oxygenated blood replacement-type fluid.

Using the perfusion machine, organs can be sustained up to 80 hours after recovery from the donor, remain viable, and often begin working immediately after transplant to the recipient.

Injured human liver treated for 3 days in a machine and then successfully transplanted Date: May 31, 2022 Source: University of Zurich Summary: A multidisciplinary research team has succeeded in ...