platelet-derived growth factor receptor (PDGFR) and bcr–abl. Because of the crucial role of the PI3K pathway in normal cell growth and in the cellular response to stress, the main challenge to ...
Immunoprecipitations identified the PI3K-activating proteins ERBB3 (an RTK ... decreased cell viability and growth. Addition of the PDGFR/KIT/ABL kinase inhibitor imatinib to the combination ...
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