A rigorous, international study published in the New England Journal of Medicine has demonstrated the presence of IgG autoantibodies that stimulate the fibroblast receptor for platelet-derived ...
Expert Rev Ophthalmol. 2013;8(6):527-537. Protein kinase C-mediated contraction of RPE cells is stopped by an anti-PDGF antibody. Unfortunately, blocking PDGF is ineffective at suppressing PVR in ...
When investigating signaling pathways and protein activation, one often stimulates the cells to promote the activation, as illustrated by platelet-derived growth factor (PDGF)-BB stimulation of ...