A rigorous, international study published in the New England Journal of Medicine has demonstrated the presence of IgG autoantibodies that stimulate the fibroblast receptor for platelet-derived ...

This article reviews previous experiences and current and future development strategies of sorafenib in breast cancer ... 2 and 3, PDGF receptors α and β, RET, Flt3, c-KIT and the RAF kinase ...

Table 1 shows a matrix of the kinase genes that carry mutations or that are overexpressed in certain types of cancer ... derived growth factor receptor (PDGFR), which lead to imatinib resistance ...

Expert Rev Ophthalmol. 2013;8(6):527-537. Protein kinase C-mediated contraction of RPE cells is stopped by an anti-PDGF antibody. Unfortunately, blocking PDGF is ineffective at suppressing PVR in ...