Discovery of growth factor and receptor mechanism in brain could improve stroke care
The study, published in the Journal of Clinical Investigation, shows that the growth factor PDGF-CC and its receptor PDGFRα ...
Nature5y
Strong evidence that anti-PDGFR antibodies cause scleroderma
A rigorous, international study published in the New England Journal of Medicine has demonstrated the presence of IgG autoantibodies that stimulate the fibroblast receptor for platelet-derived ...
pharmaphorum5y
Bayer's regorafenib kicks off brain cancer platform trial
Bayer has become the first pharma company to take part in a new platform trial designed to find new treatments for brain cancer ... BRAF), metastasis (VEGFR3, PDGFR, FGFR) and tumour immunity ...
Medscape10d
PDGF: Ophthalmology's Next Great Target
Expert Rev Ophthalmol. 2013;8(6):527-537. Protein kinase C-mediated contraction of RPE cells is stopped by an anti-PDGF antibody. Unfortunately, blocking PDGF is ineffective at suppressing PVR in ...