Discovery of growth factor and receptor mechanism in brain could improve stroke care
Researchers at Karolinska Institutet have identified a new mechanism that may improve the treatment of ischemic stroke. The ...
Mirage News10d
New Findings Could Improve Stroke Care
Researchers at Karolinska Institutet have identified a new mechanism that may improve the treatment of ischemic stroke. The ...
pharmaphorum5y
Bayer's regorafenib kicks off brain cancer platform trial
Bayer has become the first pharma company to take part in a new platform trial designed to find new treatments for brain cancer ... BRAF), metastasis (VEGFR3, PDGFR, FGFR) and tumour immunity ...
Nature4mon
Widening the therapeutic window?
In mice, middle cerebral artery occlusion (MCAO; a stroke model) resulted in a twofold increase in PDGFR-α phosphorylation in the ischaemic hemisphere of the brain, an effect that was not ...
Nature5y
Strong evidence that anti-PDGFR antibodies cause scleroderma
A rigorous, international study published in the New England Journal of Medicine has demonstrated the presence of IgG autoantibodies that stimulate the fibroblast receptor for platelet-derived ...
Medscape2mon
Immune Modulation And Increased Neurotrophic Factor Production In Multiple Sclerosis Patients Treated With Testosterone
Furthermore, PBMCs obtained during the treatment period produced significantly more BDNF and PDGF-BB. Conclusion ... cognitive function improved and the brain atrophy rate was significantly ...