Recently, a new substrate that is activated by tPA was identified — PDGF-CC — which triggers PDGF receptor-α (PDGFR-α) signalling within the CNS. The authors therefore proposed that the tPA ...

2). Wild-type PAE cells do not express human PDGFR, PAE-α cells express human PDGFR-α, and PAE-β cells express human PDGFR-β. Duolink reagents and two primary antibodies, one targeting human ...