Brain tumours remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than ...

Brain tumors remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than ...

A study shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States Food and Drug ...

Koschmann and his collaborators targeted PDGFRA, which is one of the most commonly mutated ... of drugs entering brain tumors like this and shutting down key oncogenic pathways. These results support ...

High-grade glioma, a difficult-to-treat and aggressive form of pediatric and adult brain cancer, responded to FDA-approved avapritinib. | Drug Discovery And Development ...

At the same time, the team also made the surprising discovery that endocan interacts with a receptor on glioblastoma cells called PDGFRA, activating pathways that promote tumor growth and ...

Koschmann and his collaborators targeted PDGFRA, which is one of the most commonly mutated ... of drugs entering brain tumors like this and shutting down key oncogenic pathways. These results support ...

RECKGIST score may predict recurrence in neurofibromatosis type 1 GISTs, potentially guiding treatment decisions, according ...

Koschmann and his collaborators targeted PDGFRA, which is one of the most ... brain tumors like this and shutting down key oncogenic pathways. These results support a lot of ongoing efforts ...