PDGF-B secreted from skeletal muscle cells enhances not only cell proliferation but also muscle hypertrophy accompanied by contractile function.

USA), a 50 kDa aptamer that binds to PDGF-B. A Phase I escalating dose trial enrolled 57 patients with advanced exudative AMD. Patients were given a single dose of 0.03 mg fovista with 3 monthly ...

So, it seems that growth factors such as PDGF can instruct cortical progenitor ... Owing to this dual effect, the activation of the MEK–CEBP pathway might be a mechanism whereby growth factors ...