As a proof-of-principle, we screened human endothelial cells stimulated with vascular endothelial growth factor (VEGF) and constructed a peptide-based ligand-receptor map of the VEGF family.

The ability of tumours to induce new blood-vessel formation has been a major focus of cancer research over the past few decades, and vascular endothelial growth factor (VEGF) is now known to be ...

Sorafenib is an oral tyrosine kinase inhibitor able to inhibit VEGF receptors 1, 2 and 3, PDGF receptors α and β, RET, Flt3, c-KIT and the RAF kinase and MAPK pathways. Over 10,000 patients have ...

AGE, advanced glycation end product; PDGF, platelet-derived growth factor; ROP, retinopathy of prematurity; ROS, reactive oxygen species; VEGF, vascular endothelial growth factor. Hans-Peter ...

The key mechanisms include: Cell proliferation: Growth factors such as platelet-derived growth factor (PDGF) and transforming ... Vascular endothelial growth factor (VEGF) promotes the formation ...

Vascular Endothelial Growth Factor A (VEGFA) is a member of the PDGF/VEGF growth factor family. It is an angiogenic and neurotrophic factor, secreted by endothelial cells, and is known to impact ...