Human RPE cells become less viable and express VEGF and PDGF when exposed to light ... are not likely to be used for the long-term treatment of exudative AMD. Monoclonal antibodies generally ...

Researchers at Karolinska Institutet have identified a new mechanism that may improve the treatment of ischemic stroke. The study, published in the Journal of Clinical Investigation, shows that the ...

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PDGF and its receptors are implicated in tumorigenesis and angiogenesis, prompting Sebti and colleagues to design a synthetic molecule, called GFB-111, that binds to PDGF. Their new molecule has ...

Sorafenib is an oral tyrosine kinase inhibitor able to inhibit VEGF receptors 1, 2 and 3, PDGF receptors α and ... Sorafenib is US FDA approved for the treatment of advanced renal cell carcinoma ...