PDGF stimulates the proliferation and migration of pericytes, vascular smooth muscle cells and fibroblasts. Newly formed blood vessels become stable without further dependence on VEGF when ...

PDGF and its receptors are implicated in tumorigenesis and angiogenesis, prompting Sebti and colleagues to design a synthetic molecule, called GFB-111, that binds to PDGF. Their new molecule has ...