However, tumor vasculature is abnormal, chaotic and leaky due to the high production of angiogenic factors such as VEGF. In tumors, Dll4/Notch signaling appears to dampen (much like a resistor in ...

Two independent studies show that ephrin-B2 controls the internalization and signaling of two types of vascular endothelial growth factor (VEGF) receptors—thereby regulating VEGF-induced ...