N: No; Y: Yes. Many of the genes associated with hereditary forms of Parkinson's disease have been identified. They appear to function in protein processing and/or mitochondrial activity.

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death. Mitochondrial Ca2+ (Ca2+mito) plays a dual role in physiological processes ...

Regardless of the cell type, the researchers found that damage to the mitochondria did not cause cell death. This observation ...

Sep. 24, 2024 — Parkinson's disease, a debilitating nervous system ... for researchers to boost mitophagy activity, to promote mitochondrial and neuronal ... July 8, 2024 — By prohibiting ...

In a groundbreaking development for neurological care, scientists have unveiled an artificial intelligence-powered blood test that has the potential to detect Parkinson’s disease years before ...

Inhibikase Therapeutics announced disappointing results from a Phase 2 trial for its Parkinson’s disease drug, risvodetinib, ...

Biotin supplementation reversed neurotoxicity in flies and iPSC-derived neurons, improving mitochondrial function ... rescues manganese-induced Parkinson's disease phenotypes and neurotoxicity ...

Researchers in India have developed a new nanoformulation that may improve the safety and efficacy of Parkinson's disease treatment, IANS, a partner ...

We plan to evaluate different biomarkers of Parkinson’s disease from the cerebrospinal fluid and plasma ... to other cellular compartments including the endoplasmic reticulum and mitochondria. We have ...