Diuretic efficiency -- cumulative weight change per cumulative loop diuretic dose -- wasn't significantly better with the SGLT2 inhibitor (SGLT2i) than with standard diuretic titration (OR 0.65 ...

After adjustment for baseline weight, researchers observed no difference in diuretic efficiency between early dapagliflozin and usual care (OR = 0.65; 95% CI, 0.41-1.02; P = .06); however, early ...

This was structured standard of care, so we standardized the IV loop diuretic regimen that patients received so both treatment arms were titrated to a goal urine output of 3 to 5 liters per day ...

Loop diuretics are an essential component of therapy for patients with acute decompensated heart failure, ... or a Cox model and Kaplan–Meier curves (for time-to-event end points).

The findings of DICTATE-AHF have several implications for cardiologists treating patients with type 2 diabetes, said Zachary Cox, PharmD, professor at Lipscomb University College of Pharmacy.