It will be interesting to determine whether this pathway plays a role in the detection of other Gram-negative bacteria and whether caspase-11 activation by intracellular bacteria might also depend ...

However, compared with intracellular SQSTM1, the molecular mechanism of innate immunity mediated by extracellular SQSTM1 remains unclear. This prompted the new study co-led by Kang, Daoling Tang, an ...

Coxiella burnetii is the Gram-negative obligate intracellular pathogen that causes Q fever, a condition which presents as either acute or chronic disease ().Phylogenetic analyses have shown that ...