The results of an early trial in 31 brain cancer patients finds immune activity boosted in the tumor, and possibly longer survival. Amid cuts to federal funding, US universities tighten budgets, ...

However, we have a group of ‘essential genes’ that we cannot remove because it results in cell death.” To overcome this, Adli and colleagues utilize reversible auxin-inducible degron (AID) tools that ...

It seems that proteins called hypoxia-inducible factors (HIFs) can affect gene expression in low-oxygen conditions. While some control of gene expression is mediated through control of whether a ...

Shipra Das, an immunooncologist at Cellectis, discussed a novel approach using transcription activation-like effector nucleases (TALENs) gene editing to overcome these shortcomings by making CAR T ...

A new study in the Journal of Interferon & Cytokine Research (JICR) showed that a specific retinoic acid-inducible gene I (RIG-I) agonist RNA (RAR) induces innate immune signaling and death of ...

New Rochelle, NY, February 19, 2025—A new study in the peer-reviewed Journal of Interferon & Cytokine Research (JICR) showed that a specific retinoic acid-inducible gene I (RIG-I) agonist RNA ...