Rolling Out5d
How 5 powerful myokines reshape your body when you exercise
Research reveals how exercise triggers the release of specialized myokines that regulate metabolism, build muscle, reduce ...
Kaleido Scope9y
Program in Immunology
Beatriz Leon-Ruiz, Ph.D. In a study published in the Nature Journal Cellular & Molecular Immunology, Beatriz Leon-Ruiz, PhD and colleagues report an unrecognized mechanism of how interrupted IL-6 ...
Nature14y
The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival
IL-6 and downstream JAK-dependent signaling pathways have critical roles in the pathophysiology of multiple myeloma (MM). We investigated the effects of a novel small-molecule JAK inhibitor ...