With the final step in HIF pathway established, scientists began to explore ways to utilize it. Because the hypoxia response is present across all tissues and cell types, the HIF pathway drives ...

NOTCH signaling influences these traits through interactions with other pathways like TGF-β, WNT, and hypoxia signaling. The ...

"We are very much interested in identifying pathways that are working independently of the pathway in this research to further understand how certain genes can be turned on upon hypoxia." ...

Cancer remains a leading cause of death globally, with lung cancer being particularly lethal. Despite advancements in diagnostics and therapies, the five-year survival rates for advanced tumors have ...

Background Mechanical stress on the heart is commonly considered the sole stimulus explaining the synthesis and release of circulating natriuretic peptides and their derivatives. While one of the most ...

By adding the stress of hypoxia during ‘aerobic’ or ‘anaerobic’ interval training, it is believed that IHT would potentiate greater performance improvements compared to similar training at sea level.