2006). Using DNA microarrays, these investigators examined changes in gene expression at a global level in different cell types. In looking for a signature of hypoxia, the researchers compared ...

Background Mechanical stress on the heart is commonly considered the sole stimulus explaining the synthesis and release of circulating natriuretic peptides and their derivatives. While one of the most ...

Yet for decades the precise workings were largely a mystery. Scientists knew that in low oxygen situations, or hypoxia, cells trigger a cascade of physiological events to restore oxygen ...

Hypoxia limits T-cell infiltration and suppresses immune responses, especially in prostate, pancreatic, and head and neck cancers. “By reversing hypoxia, IMGS-101 may restore T-cell access to ...

Their paper is published in the European Heart Journal. "Microvascular over-dilation causes hypoxia and cell shrinkage even in healthy muscle," Korpisalo notes. In light of the new findings ...

This condition, which often occurs during medical events such as heart failure, can also cause acute altitude sickness; ...

By lowering the media volume, and thus increasing the pericellular oxygen, Tan observed lowered hypoxia signaling and transcriptional rewiring that recapitulated a healthier adipocyte cell model.

Antibiotics increase the gut oxygen levels and favor growth of harmful fungi. Chemically restoring intestinal gut hypoxia ...

By adding the stress of hypoxia during ‘aerobic’ or ‘anaerobic’ interval training, it is believed that IHT would potentiate greater performance improvements compared to similar training at sea level.