How Omeprazole Works. Medically reviewed by Alisha D. Sellers, BS Pharmacy, PharmD — Written by Helen Marshall, BPharm, MRPharmS on May 2, 2025. How it works; How long it takes to work; ...

Omeprazole works by inhibiting the proton pump, which is responsible for strong acid in the stomach. Dr. Keith Roach Oct 5, 2023 6:30 AM. Share by Email. Share on Facebook. Share on X.