Enhancement of HIV-1 Infectivity. Early work on this topic ... protein other than CD4 that blocks the function of Env in the virion. Nef enhances infectivity by downregulating this unknown protein ...
The resulting complex of viral cDNA and virion proteins, now referred to as the pre-integration complex (PIC), is transported to the nucleus (Fig. 1). Figure 1: Models of flap-dependent HIV ...
Figure 1: The HIV-1 glycoprotein gp120 minimizes the exposure of protein surface to antibody recognition on the envelope spike on the surface of the virion. Why have some viruses apparently ...
HIV-1 Vif induces a unique and prolonged pseudo-metaphase arrest by disrupting phosphatase feedback regulation at the kinetochore.
Dr. Ochsenbauer-Jambor investigates the role of DC-SIGN in the capture and trans-infection of HIV-1 with special emphasis on virion internalization pathways and the acquisition of selective ...
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