On Tuesday, the team behind the plan to bring mammoth-like animals back to the tundra announced the creation of what it is ...

These systems, which the researchers call TIGR (Tandem Interspaced Guide RNA) systems, use RNA to guide them to specific sites on DNA. TIGR systems can be reprogrammed to target any DNA sequence ...

But to date this technology - which allows scientists to use a "guide" RNA to modify DNA sequences and evaluate the effects - ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Researchers have identified an ancient RNA-guided system that can target DNA, potentially expanding the genome-editing toolbox.

Bioengineering professor and The Grainger College of Engineering's Dean, Rashid Bashir, led a team of researchers in a ...

For discussion questions and lesson plans, go to the RNA Lab collection on PBS LearningMedia. The standards-based NOVA RNA Lab allows users to explore the science of RNA and learn how to design ...

Editing RNA isn’t all that different from DNA base-editing techniques, which typically use Cas9 or other enzymes attached to a CRISPR guide RNA to replace one nucleotide with another. In the case of ...

RNA sequencing is a powerful tool that helps researchers uncover novel biological insights into the transcriptome. This free eBook allows readers to learn about RNA sequencing (RNA-Seq) by ...

Our investigations of exosomes in budding yeast revealed that its central channel is essential, and that it functions to guide RNA substrates to the active sites of both Dis3 and Rrp6. We subsequently ...