Every person carries two copies of most genes, with one version, or allele, coming from each parent. Even though these copies tend to be functionally redundant, conventional genetic theory dictates ...

Relative allele frequency is the percentage of all copies of a certain gene in a population that carry a specific allele. This is an accurate measurement of the amount of genetic variation in a ...

Somatic cells contain two alleles for every gene, with one allele provided by each parent of an organism. Often, it is impossible to determine which two alleles of a gene are present within an ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA ...

2005;50(3):184-188. For example, in a white population, the most common deleterious allelic variant in the CFTR gene is CFTR delta F508 allele, resulting in the absence of a single amino acid ...

Gene editing has taken root in plant breeding, leading to numerous advances in plant-based foods. K-State scientists, for ...

Then, the team sequenced the STING gene in every patient and relative ... "It's the first report of a common allele providing total protection from a severe genetic disorder." HAQ-STING clears a path ...

A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.

The study demonstrated that cells in 14 brain regions, including multiple parts of the hypothalamus, which helps coordinate the endocrine system, specifically express the maternal allele for the gene ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene ...