Allopurinol and febuxostat were both associated with lower all-cause mortality when used by adults undergoing hemodialysis in Japan; allopurinol also lowered risk of death from CVD events ...

Subgroup analysis, however, demonstrated that febuxostat was associated with a significant suppression of eGFR decline compared with placebo among patients without proteinuria (1.69 vs ˗0.10) and ...

Indeed, the hazard ratio comparing febuxostat use with no ULT was 1.07 (95% CI, 0.99-1.16), reported study investigator Richard Partington, MBChB, MSc, PhD, a general practitioner in Morecambe ...

Febuxostat oral tablet is a prescription medication used to treat hyperuricemia (high levels of uric acid) in adults with gout. It helps decrease symptoms of gout. The tablet is available only as ...

For the febuxostat group, sUA (mean ± standard deviation) was 5.65 ± 1.35mg h/dL at baseline, 3.08 ± 1.34mg h/dL at Day 3, and 2.55 ± 1.20mg h/dL at Day 6.

Beside reducing serum uric acid in patients with chronic kidney disease (CKD), febuxostat may preserve kidney function, investigators report. In a trial, investigators randomly assigned 84 ...

Febuxostat is a xanthine oxidase (XO) inhibitor, prescribed for gout and hyperuricemia (high level of uric acid in blood). Febuxostat Interaction with 12 drugs. Find out more in the list below: ...

Febuxostat, a nonpurine inhibitor of xanthine oxidase that is used for the management of hyperuricemia in patients with gout, inhibits both the oxidized and reduced forms of xanthine oxidase and ...

Both allopurinol and febuxostat carry similar, significant increased risks for hypersensitivity reactions compared with colchicine, according to data published in Annals of the Rheumatic Diseases ...

Effects of Febuxostat in Early Gout: A Randomized, Double-blind, Placebo-controlled Study. Arthritis & Rheumatology , 2017; DOI: 10.1002/art.40233 Cite This Page : ...

To the Editor: The article by Becker et al. (Dec. 8 issue)1 includes an inaccurate and misleading statement regarding the comparison of 80 mg per day of febuxostat with allopurinol for gout. The a ...

Presenting phase 3 data from the study known as APEX, Wortmann said this is the longest and largest controlled clinical trial of gout. The researchers looked at more than 1000 patients with serum ...