It has been shown to work in two FLT3 mutations – namely ITD and TKD – while quizartinib only targets ITD but has greater potency against that target. Xospata and quizartinib have reached the ...

Two FLT3-WT patients achieved complete remissions after Cycle 1, while another showed significant blast reduction and remains in therapy. Find out which stock just plummeted to the bottom of the ...

The two factors cooperate and bind to their target genes together, but only in the presence of growth factor signalling. The drugs targeting FLT3 rewire the cell, resulting in the upregulation of ...