A group of scientists led by Pennington Biomedical Research Center's Dr. Christopher Morrison has discovered that the hormone fibroblast growth factor 21 (FGF21) plays an influential role in brain ...

A group of scientists recently discovered that the hormone fibroblast growth factor 21, or FGF21, plays an influential role in brain reward mechanisms like those involved in dietary choices.

Boehringer Ingelheim GmbH terminated its second metabolic dysfunction-associated steatohepatitis (MASH) alliance on March 6, ...

Fibroblast growth factor 21 (FGF21) analogs significantly improve fibrosis and resolve metabolic dysfunction-associated steatohepatitis (MASH) without progression, showing promise for non ...

The results of a phase 2b ENLIVEN trial of FGF21 analogue pegozafermin showed it was able to reduce scarring (fibrosis) in the liver of NASH patients at more than three times the rate of a placebo ...

FGF19 analog (Aldafermin) and FGF21 receptor agonist (Pegbelfermin) also promise to reduce liver fat and improve liver function. In preclinical studies, the THR-β agonist Resmetirom helps ...

confirming that FGF21 ameliorated MASH progression through the autocrine signaling pathway mediated by the FGFR/βKlotho receptor complex in hepatocytes. By employing protein interaction mass ...

Boehringer Ingelheim GmbH terminated its second metabolic dysfunction-associated steatohepatitis (MASH) alliance on March 6, ending an $870 million license agreement inked with Yuhan Corp. for dual ...