Fibroblast growth factor 21 (FGF21) analogs significantly improve fibrosis and resolve metabolic dysfunction-associated steatohepatitis (MASH) without progression, showing promise for non ...

A group of scientists led by Pennington Biomedical Research Center's Dr. Christopher Morrison has discovered that the hormone fibroblast growth factor 21 (FGF21) plays an influential role in brain ...

The results of a phase 2b ENLIVEN trial of FGF21 analogue pegozafermin showed it was able to reduce scarring (fibrosis) in the liver of NASH patients at more than three times the rate of a placebo ...

A group of scientists recently discovered that the hormone fibroblast growth factor 21, or FGF21, plays an influential role in brain reward mechanisms like those involved in dietary choices.

While fibroblast growth factor 21 (FGF21) analogs have shown promise in clinical trials, their underlying molecular mechanisms remain unclear. A research team led by Prof. Li Yu at the Shanghai ...

Two studies have now identified that the peptide hormone FGF21 acts on thymic epithelial cells to delay age-associated thymic involution and T cell imbalance. PROX1 acts as a molecular ‘cell ...