It works by blocking the hormone endothelin from binding to receptors in blood vessels, preventing those blood vessels from constricting. Tryvio is the first endothelin receptor antagonist for ...

The researchers examined the effect of three antioxidants—luteolin, hesperetin, and diosmetin—on mice specially bred to gray ...

The endothelins are a family of potent vasoconstrictors. The important biological functions of endothelin are mediated by the endothelin type-A and endothelin type-B receptors, encoded by the ...